Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.62 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.62 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.62 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 5/20 | 0.48 |
| ▸ | CDC25A | P30304 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | MITF | O75030 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627830 | 0.81 | CDC25A (0.49) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| SCHEMBL9627565 | 0.80 | IDO1 (0.54) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| Dichlon SCHEMBL29360991 | 0.78 | IDO1 (1.00) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| Dichlon SCHEMBL9751236 | 0.78 | IDO1 (1.00) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| Dichlon SCHEMBL45723 | 0.78 | IDO1 (1.00) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| SCHEMBL31267509 | 0.78 | CES2 (0.39) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| Dichlon SCHEMBL10794085 | 0.76 | IDO1 (0.94) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| Dichlon SCHEMBL5077878 | 0.76 | IDO1 (0.94) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| SCHEMBL22874151 | 0.76 | CDC25B (0.54) | IDO1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9324815 | 0.75 | IDO1 (0.58) | IDO1DNMT1DNMT3LDNMT3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |
| US-4507241-A | Method for the hydrocarbylation of naphthoquinone derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-03-26 | — | — | US | disclosed |