Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | RARG | P13631 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628652 | 0.86 | RARB (0.62) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL3798800 | 0.84 | ALOX5 (0.56) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL27496708 | 0.82 | KMT2A (0.64) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL7823497 | 0.81 | ALOX5 (0.73) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL4186122 | 0.80 | KDM4E (1.00) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL13801095 | 0.76 | KDM4E (0.68) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL9620801 | 0.74 | LMNA (0.51) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL9555334 | 0.72 | ALOX5 (0.52) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL7324615 | 0.71 | CA1 (0.65) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL13442817 | 0.71 | MAPT (0.60) | KMT2AMEN1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124342-A | Antiinflammatory, antiarthritic agents; antiallergens; skin disorders | ABBOTT LABORATORIES (US) | 1992-06-23 | — | — | US | disclosed |
| WO-1990009801-A1 | 4-HYDROXYTHIAZOLES AS 5-LIPOXYGENASE INHIBITORS | ABBOTT LABORATORIES (US) | 1990-09-07 | — | — | WO | disclosed |