Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620838 | 0.89 | RARA (0.47) | LMNARAB9AKMT2AALDH1A1NPC1 | |
| SCHEMBL9620538 | 0.89 | DYRK1A (0.54) | LMNARAB9AKMT2AALDH1A1NPC1 | |
| SCHEMBL9621138 | 0.85 | SMN1; SMN2 (0.52) | LMNARAB9AKMT2AALDH1A1NPC1 | |
| SCHEMBL1223274 | 0.85 | APP (0.44) | LMNARAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL9620668 | 0.83 | APP (0.64) | LMNARAB9AKMT2AALDH1A1NPC1 | |
| SCHEMBL6219086 | 0.81 | BACE1 (0.49) | KMT2AALDH1A1NPC1MEN1MAPT | |
| SCHEMBL9620871 | 0.79 | DYRK1A (0.53) | LMNARAB9AKMT2AALDH1A1NPC1 | |
| SCHEMBL3374002 | 0.76 | RAB9A (0.63) | LMNARAB9AKMT2AALDH1A1NPC1 | |
| SCHEMBL9628036 | 0.74 | KMT2A (0.67) | LMNARAB9AKMT2AALDH1A1NPC1 | |
| SCHEMBL1038556 | 0.72 | DYRK1A (0.78) | LMNARAB9AKMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306708-B1 | NOVEL BENZOTHIAZOLE AND ANTIRHEUMATIC AGENT COMPRISING IT AS AN ACTIVE INGREDIENT | KANEBO, LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4910211-A | Containing a phenyl substituted in position 2 and an ester in position 4 | KANEBO LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0306708-A1 | Novel benzothiazole and antirheumatic agent comprising it as an active ingredient | KANEBO, LTD. (JP) | 1989-03-15 | — | — | EP | disclosed |