Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612242 | 0.90 | MRGPRX4 (0.53) | HDAC6MAPTMRGPRX4ALOX5SMN1; SMN2 | |
| SCHEMBL17912883 | 0.89 | LMNA (0.45) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL7705106 | 0.85 | MAPT (0.50) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL17912858 | 0.85 | ACLY (0.47) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL10823520 | 0.83 | ELANE (0.46) | — | |
| SCHEMBL10422130 | 0.82 | CASP3 (0.61) | CYP2C19MAPTL3MBTL1TDP1MRGPRX4 | |
| SCHEMBL14283740 | 0.81 | CYP2C19 (0.53) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL29018842 | 0.79 | SMN1; SMN2 (0.49) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL29380769 | 0.78 | MAPT (0.57) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL416462 | 0.78 | MAPT (0.57) | CYP2C19LMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |