SCHEMBL416462

SCHEMBL416462

c1ccc(COc2ccc(OCc3ccccc3)c3ccccc23)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
MAPK1 P28482 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HTR1A P08908 1/20 0.53
DRD2 P14416 1/20 0.53
MRGPRX4 Q96LA9 2/20 0.53
LIPE Q05469 1/20 0.52
PLAU P00749 1/20 0.51
PLAT P00750 1/20 0.51
TSHR P16473 1/20 0.50
ALOX5 P09917 1/20 0.50
GPR84 Q9NQS5 1/20 0.50
LTA4H P09960 1/20 0.50
MAPK14 Q16539 1/20 0.50
F2 P00734 1/20 0.49
ALPG P10696 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29380769 1.00 MAPT (0.57) MAPTL3MBTL1MAPK1TDP1NPC1
SCHEMBL3157216 0.90 MRGPRX4 (0.66) MAPTL3MBTL1MAPK1TDP1NPC1
SCHEMBL10607164 0.90 HTR1A (0.58) MAPTL3MBTL1MAPK1TDP1NPC1
SCHEMBL1356852 0.88 GPR84 (0.51) MAPTL3MBTL1MAPK1TDP1NPC1
SCHEMBL30250452 0.88 GPR84 (0.51) MAPTL3MBTL1MAPK1TDP1NPC1
SCHEMBL2024384 0.88 IDO1 (0.61) MAPTL3MBTL1MAPK1TDP1NPC1
SCHEMBL4074725 0.88 IDO1 (0.53) MAPTL3MBTL1MAPK1TDP1NPC1
SCHEMBL17736774 0.88 CYP2D6 (0.48) MAPTL3MBTL1MAPK1TDP1NPC1
SCHEMBL10605182 0.87 HTR1A (0.51) MAPTL3MBTL1MAPK1TDP1NPC1
SCHEMBL10719571 0.85 MAPT (0.49) MAPTL3MBTL1MAPK1TDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61051383-A None JP disclosed
JP-62280072-A None JP disclosed
JP-63247085-A None JP disclosed
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method RICOH COMPANY, LTD. (JP) 2026-05-12 US disclosed
WO-2026087975-A1 THERMOSENSITIVE RECORDING MEDIUM AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2026-04-30 WO disclosed
EP-4022391-B1 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2026-03-04 EP disclosed
EP-4676749-A1 THERMOSENSITIVE RECORDING MEDIUM, METHOD FOR PRODUCING THERMOSENSITIVE RECORDING MEDIUM, AND ARTICLE COMPRISING THE THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2026-01-14 EP disclosed
EP-4420887-B1 THERMOSENSITIVE RECORDING MEDIUM RICOH CO LTD (JP) 2025-10-15 EP disclosed
US-20250289259-A1 THERMOSENSITIVE RECORDING MEDIUM FOR LINERLESS LABEL RICOH COMPANY, LTD. (JP) 2025-09-18 US disclosed
US-20250162340-A1 THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2025-05-22 US disclosed
US-5043313-A Mixture of leuco dye and diphenyl polyhydroxy sulfone compound RICOH COMPANY, LTD. (JP) 1991-08-27 US disclosed
US-5008238-A Thermosensitive material with phenolic developer RICOH COMPANY, LTD. (JP) 1991-04-16 US disclosed
US-4985394-A LEUCO DYE, PROTECTIVE LAYER OF SILICA AND CALCIUM CARBONATE AND WATER SOLUBLE BINDER, GLOSS RICOH COMPANY, LTD. (JP) 1991-01-15 US disclosed
US-4985345-A LEUCO DYES, BAR CODE READER RICOH COMPANY, LTD. (JP) 1991-01-15 US disclosed
EP-0189760-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1989-07-19 EP disclosed
JP-S63247085-A THERMAL RECORDING MATERIAL HONSHU PAPER CO LTD 1988-10-13 JP disclosed
US-4721701-A Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-01-26 US disclosed
JP-S62280072-A THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD 1987-12-04 JP disclosed
EP-0189760-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-08-06 EP disclosed
JP-S6151383-A THERMAL RECORDING PAPER NIPPON SHOKUBAI KAGAKU KOGYO CO LTD 1986-03-13 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method TRPA1, ASIC1, LRBA MAPT 1312/4885L3MBTL1 664/4885MAPK1 308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.