Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 8/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487002 | 0.87 | TAAR1 (0.45) | SLC6A4TAAR1CYP2D6 | |
| SCHEMBL678668 | 0.82 | MPO (0.50) | MPOSLC6A4HSPA5TAAR1MGLL | |
| SCHEMBL28957063 | 0.80 | MPO (0.49) | MPOSLC6A4HSPA5TAAR1MGLL | |
| SCHEMBL18807140 | 0.79 | MPO (0.47) | MPOSLC6A4HSPA5TAAR1MGLL | |
| SCHEMBL4740026 | 0.78 | CYP2D6 (0.54) | SLC6A4HSPA5TAAR1POLBMAPK1 | |
| SCHEMBL15570944 | 0.78 | CYP2D6 (0.54) | SLC6A4HSPA5TAAR1POLBMAPK1 | |
| SCHEMBL31611864 | 0.78 | CYP2D6 (0.54) | SLC6A4HSPA5TAAR1POLBMAPK1 | |
| SCHEMBL11573650 | 0.78 | MGLL (0.44) | MPOSLC6A4HSPA5TAAR1MGLL | |
| SCHEMBL7332508 | 0.77 | MPO (0.46) | MPOSLC6A4HSPA5TAAR1MGLL | |
| SCHEMBL9627286 | 0.77 | TAAR1 (0.50) | MPOTAAR1CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |