Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24919879 | 0.84 | HTR2B (0.64) | HTR2B | |
| SCHEMBL2090208 | 0.81 | APEX1 (0.50) | APEX1HTR2B | |
| SCHEMBL28077207 | 0.81 | ALDH1A1 (0.46) | APEX1 | |
| SCHEMBL2090207 | 0.79 | APEX1 (0.48) | APEX1HTR2B | |
| SCHEMBL12209850 | 0.77 | NPC1 (0.45) | APEX1HTR2B | |
| SCHEMBL9630548 | 0.76 | ALOX5 (0.62) | — | |
| SCHEMBL9629598 | 0.75 | — | — | |
| SCHEMBL9629483 | 0.73 | ALOX5 (0.58) | — | |
| SCHEMBL9629266 | 0.73 | ALOX5 (0.63) | — | |
| SCHEMBL13801079 | 0.72 | ALDH1A1 (0.52) | APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124342-A | Antiinflammatory, antiarthritic agents; antiallergens; skin disorders | ABBOTT LABORATORIES (US) | 1992-06-23 | — | — | US | disclosed |
| EP-0457803-A4 | 4-HYDROXYTHIAZOLES AS 5-LIPOXYGENASE INHIBITORS | — | 1991-12-04 | — | — | EP | disclosed |
| EP-0457803-A1 | 4-HYDROXYTHIAZOLES AS 5-LIPOXYGENASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-11-27 | — | — | EP | disclosed |
| WO-1990009801-A1 | 4-HYDROXYTHIAZOLES AS 5-LIPOXYGENASE INHIBITORS | ABBOTT LABORATORIES (US) | 1990-09-07 | — | — | WO | disclosed |
| WO-1990009381-A1 | 4-HYDROXYTHIAZOLES AS 5-LIPOXYGENASE INHIBITORS | ABBOTT LABORATORIES (US) | 1990-08-23 | — | — | WO | disclosed |