SCHEMBL13801079

SCHEMBL13801079

Fc1ccccc1-c1nc2sc(-c3ccccc3F)nc2s1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
KDM4E B2RXH2 2/20 0.52
S1PR1 P21453 1/20 0.49
MPL P40238 1/20 0.46
NPC1 O15118 6/20 0.41
DCUN1D1 Q96GG9 2/20 0.41
F2RL3 Q96RI0 1/20 0.41
GUSB P08236 1/20 0.41
APEX1 P27695 1/20 0.41
RAB9A P51151 5/20 0.40
PKM P14618 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
RXFP1 Q9HBX9 1/20 0.40
F2 P00734 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
DCTPP1 Q9H773 1/20 0.39
MEN1 O00255 1/20 0.39
NFKB1 P19838 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26500156 0.85 KDM4E (0.43) ALDH1A1KDM4ES1PR1MPLNPC1
SCHEMBL11646035 0.78 POLB (0.57) ALDH1A1KDM4ES1PR1NPC1RAB9A
SCHEMBL13801086 0.76 HSD17B10 (0.44) ALDH1A1KDM4ENPC1DCUN1D1RAB9A
SCHEMBL9313715 0.76 HTR2B (0.53) ALDH1A1KDM4ENPC1DCUN1D1GUSB
SCHEMBL13801072 0.76 ALDH1A1 (0.42) ALDH1A1KDM4ENPC1DCUN1D1RAB9A
SCHEMBL28077207 0.75 ALDH1A1 (0.46) ALDH1A1KDM4ES1PR1MPLNPC1
SCHEMBL2138149 0.75 KDM4E (0.66) ALDH1A1KDM4ENPC1RAB9AL3MBTL1
SCHEMBL2090208 0.75 APEX1 (0.50) ALDH1A1KDM4ES1PR1MPLNPC1
SCHEMBL13801112 0.74 ALOX15 (0.50) ALDH1A1KDM4EDCTPP1
SCHEMBL27750783 0.74 KDM4E (0.64) ALDH1A1KDM4ENPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-06-18 US disclosed
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT ELP1, ELAVL1, ELF3 ALDH1A1 1089/4885KDM4E 1648/4885S1PR1 4107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.