Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MPL | P40238 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28077372 | 0.87 | SLC9A1 (0.35) | ALDH1A1KDM4EALOX5NPC1RAB9A | |
| SCHEMBL9628660 | 0.81 | APEX1 (0.48) | APEX1 | |
| SCHEMBL28077415 | 0.79 | TRPM8 (0.50) | ALDH1A1KDM4EALOX5NPC1RAB9A | |
| SCHEMBL28077397 | 0.78 | GRM2 (0.37) | KDM4EALOX5SMN1; SMN2MAPTS1PR1 | |
| SCHEMBL13801079 | 0.75 | ALDH1A1 (0.52) | ALDH1A1KDM4EMPLNPC1RAB9A | |
| SCHEMBL1954805 | 0.74 | ALOX5 (0.56) | ALDH1A1ALOX5MEN1KMT2A | |
| SCHEMBL28077209 | 0.71 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL28077336 | 0.70 | HDAC9 (0.39) | ALOX5MAPT | |
| SCHEMBL2138149 | 0.69 | KDM4E (0.66) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2090208 | 0.69 | APEX1 (0.50) | ALDH1A1KDM4EMPLNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334544-B | Benzimidazole proline derivative | 埃科特莱茵药品有限公司 | 2016-10-19 | — | — | CN | disclosed |