Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 12/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28077371 | 0.83 | TRPM8 (0.64) | TRPM8 | |
| SCHEMBL2094527 | 0.83 | DCK (0.53) | TRPM8 | |
| SCHEMBL9629424 | 0.81 | TRPM8 (0.47) | TRPM8 | |
| SCHEMBL2094523 | 0.81 | ADORA3 (0.52) | TRPM8 | |
| SCHEMBL9629483 | 0.80 | ALOX5 (0.58) | — | |
| SCHEMBL9630548 | 0.79 | ALOX5 (0.62) | — | |
| SCHEMBL17374844 | 0.79 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL20845614 | 0.79 | TRPM8 (0.62) | TRPM8 | |
| SCHEMBL15057934 | 0.77 | TRPM8 (0.57) | TRPM8 | |
| SCHEMBL15049019 | 0.77 | TRPM8 (0.77) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124342-A | Antiinflammatory, antiarthritic agents; antiallergens; skin disorders | ABBOTT LABORATORIES (US) | 1992-06-23 | — | — | US | disclosed |
| EP-0457803-A4 | 4-HYDROXYTHIAZOLES AS 5-LIPOXYGENASE INHIBITORS | — | 1991-12-04 | — | — | EP | disclosed |
| EP-0457803-A1 | 4-HYDROXYTHIAZOLES AS 5-LIPOXYGENASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-11-27 | — | — | EP | disclosed |
| WO-1990009801-A1 | 4-HYDROXYTHIAZOLES AS 5-LIPOXYGENASE INHIBITORS | ABBOTT LABORATORIES (US) | 1990-09-07 | — | — | WO | disclosed |
| WO-1990009381-A1 | 4-HYDROXYTHIAZOLES AS 5-LIPOXYGENASE INHIBITORS | ABBOTT LABORATORIES (US) | 1990-08-23 | — | — | WO | disclosed |