Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016764 | 1.00 | PKM (0.52) | PKMALDH1A1TP53TSHRMEN1 | |
| SCHEMBL27130998 | 0.87 | MGLL (0.68) | PKMALDH1A1TP53TSHRMEN1 | |
| SCHEMBL8437625 | 0.86 | PKM (0.50) | PKMALDH1A1TP53TSHRMEN1 | |
| SCHEMBL13654852 | 0.86 | PKM (0.50) | PKMALDH1A1TP53TSHRMEN1 | |
| SCHEMBL8537967 | 0.86 | MGLL (0.56) | PKMALDH1A1TP53TSHRMEN1 | |
| SCHEMBL1041018 | 0.86 | PKM (0.50) | PKMALDH1A1TP53TSHRMEN1 | |
| SCHEMBL32684702 | 0.85 | MGLL (0.58) | PKMALDH1A1TP53TSHRMEN1 | |
| SCHEMBL9816004 | 0.85 | ALDH1A1 (0.54) | PKMALDH1A1TP53TSHRMEN1 | |
| SCHEMBL13433635 | 0.84 | ALDH1A1 (0.46) | PKMALDH1A1TP53TSHRMEN1 | |
| SCHEMBL32685136 | 0.83 | MGLL (0.53) | PKMALDH1A1TP53TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256586-B1 | PROCESS FOR THE PREPARATION OF ESTERS OF 4-(2,3-EPOXYPROPOXY)PHENYLACETIC ACID AND 4-(2-HYDROXY-3-ISOPROPYLAMINO-PROPOXY)PHENYLACETIC ACID AND/OR ATENOLOL IN STEREOSPECIFIC FORM | GIST-BROCADES N.V. (NL) | 1992-05-13 | — | — | EP | disclosed |