SCHEMBL1930203

SCHEMBL1930203

CC1C(C)(C)[C@@]1(Cl)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
TP53 P04637 1/20 0.36
NFKB1 P19838 1/20 0.36
CYP2C19 P33261 1/20 0.36
THPO P40225 1/20 0.36
STAT6 P42226 1/20 0.36
HIF1A Q16665 1/20 0.36
NPC1 O15118 1/20 0.36
GMNN O75496 1/20 0.36
LMNA P02545 1/20 0.36
MTOR P42345 1/20 0.36
RAB9A P51151 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
FFAR3 O14843 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6693754 0.78 FFAR3 (0.33) MAPK1SMN1; SMN2TP53NFKB1CYP2C19
Bicarbonate SCHEMBL9628771 0.77 MAPK1 (0.33) MAPK1SMN1; SMN2TP53NFKB1CYP2C19
SCHEMBL9628774 0.74 APLNR (0.31)
SCHEMBL9640788 0.72 MAPK1 (0.41) MAPK1SMN1; SMN2TP53NFKB1CYP2C19
SCHEMBL9640786 0.72 MAPK1 (0.41) MAPK1SMN1; SMN2TP53NFKB1CYP2C19
SCHEMBL11138042 0.72
SCHEMBL1376057 0.71 MAPK1 (0.44) MAPK1SMN1; SMN2TP53NFKB1CYP2C19
SCHEMBL11697745 0.70
Hydrochloric Acid SCHEMBL9639877 0.70 MAPK1 (0.39) MAPK1SMN1; SMN2TP53NFKB1CYP2C19
Fluoride SCHEMBL10972490 0.70 MAPK1 (0.39) MAPK1SMN1; SMN2TP53NFKB1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2234956-B1 CYCLOPROPANECARBOXYLATE AND PEST CONTROLLING COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL CO (JP) 2013-02-20 EP disclosed
US-7956089-B2 Cyclopropanecarboxylate and pest controlling composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-07 US disclosed
US-20100331408-A1 CYCLOPROPANECARBOXYLATE AND PEST CONTROLLING COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331408-A1 CYCLOPROPANECARBOXYLATE AND PEST CONTROLLING COMPOSITION CONTAINING THE SAME FKBP1A, CRY1, FKBP4 MAPK1 2637/4885SMN1; SMN2 2280/4885TP53 4806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.