Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.36 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627676 | 0.76 | HTR2A (0.41) | HTR2AKCNH2S1PR1TNNC1S1PR3 | |
| SCHEMBL9628818 | 0.73 | ALDH1A1 (0.46) | HTR2AKCNH2S1PR1S1PR3S1PR4 | |
| SCHEMBL30469503 | 0.68 | HTR2A (0.62) | HTR2AS1PR1TNNC1S1PR3S1PR4 | |
| SCHEMBL6861225 | 0.68 | HTR2A (0.62) | HTR2AS1PR1TNNC1S1PR3S1PR4 | |
| SCHEMBL11664454 | 0.67 | HTR2A (0.66) | HTR2AS1PR1TNNC1S1PR3S1PR4 | |
| SCHEMBL12502918 | 0.67 | HTR2A (0.66) | HTR2AS1PR1TNNC1S1PR3S1PR4 | |
| SCHEMBL1313200 | 0.67 | HTR2A (0.60) | HTR2AS1PR1TNNC1S1PR3S1PR4 | |
| SCHEMBL9945668 | 0.67 | HTR2A (0.60) | HTR2AS1PR1TNNC1S1PR3S1PR4 | |
| SCHEMBL1009348 | 0.67 | HTR2A (0.60) | HTR2AS1PR1TNNC1S1PR3S1PR4 | |
| Hydrochloric Acid SCHEMBL27921087 | 0.66 | HTR2A (0.64) | HTR2AS1PR1TNNC1S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203033-B1 | AMINO ETHYL DERIVATIVE OF BENZOTHIAZOLINTHION AS A LUBRICANT ADDITIVE | CIBA-GEIGY AG (CH) | 1992-03-11 | — | — | EP | disclosed |
| US-4810399-A | FRICTION, WEAR, CORROSION AND OXIDATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |
| US-4803001-A | RESISTANT TO FRICTION, WEAR, CORROSION AND OXIDATION | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| US-4737302-A | Aminomethyl derivatives of benzothiazolinethione as lubricant additives | CIBA-GEIGY CORPORATION (US) | 1988-04-12 | — | — | US | disclosed |