Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628831 | 0.79 | ALDH1A1 (0.63) | ALDH1A1HSD17B10CYP1A2HPGDSLC6A4 | |
| SCHEMBL9627688 | 0.79 | KCNH2 (0.39) | ALDH1A1HSD17B10CYP1A2HPGDKCNH2 | |
| SCHEMBL6741877 | 0.76 | DRD2 (0.53) | SLC6A4SLC6A3 | |
| SCHEMBL8030664 | 0.72 | DRD2 (0.52) | ALDH1A1HSD17B10CYP1A2HPGDSLC6A4 | |
| SCHEMBL11782096 | 0.69 | DRD2 (0.48) | ALDH1A1HSD17B10CYP1A2HPGDSLC6A4 | |
| SCHEMBL8088171 | 0.67 | SPHK1 (0.59) | ALDH1A1HSD17B10SPHK1THRATHRB | |
| SCHEMBL8088173 | 0.67 | SPHK1 (0.59) | ALDH1A1HSD17B10SPHK1THRATHRB | |
| SCHEMBL10732915 | 0.67 | L3MBTL1 (0.57) | ALDH1A1CYP1A2KDM4ECYP3A4 | |
| SCHEMBL854760 | 0.67 | PLK1 (0.59) | SPHK1KCNH2S1PR2S1PR4S1PR1 | |
| SCHEMBL11835323 | 0.67 | PLK1 (0.59) | SPHK1KCNH2S1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203033-B1 | AMINO ETHYL DERIVATIVE OF BENZOTHIAZOLINTHION AS A LUBRICANT ADDITIVE | CIBA-GEIGY AG (CH) | 1992-03-11 | — | — | EP | disclosed |
| US-4810399-A | FRICTION, WEAR, CORROSION AND OXIDATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |
| US-4803001-A | RESISTANT TO FRICTION, WEAR, CORROSION AND OXIDATION | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| US-4737302-A | Aminomethyl derivatives of benzothiazolinethione as lubricant additives | CIBA-GEIGY CORPORATION (US) | 1988-04-12 | — | — | US | disclosed |