Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22589962 | 0.89 | ESR1 (0.35) | RXRARXRBRXRGESR1ESR2 | |
| SCHEMBL8308767 | 0.84 | RXRA (0.36) | RXRARXRBRXRGCDC25BKDM1A | |
| SCHEMBL6939291 | 0.79 | RXRA (0.36) | RXRARXRBRXRGKDM1AALDH1A1 | |
| SCHEMBL8308844 | 0.78 | RXRA (0.43) | RXRARXRBRXRGPRKCDKDM1A | |
| SCHEMBL29518297 | 0.76 | RXRA (0.41) | RXRARXRBRXRGESR1ESR2 | |
| SCHEMBL9770756 | 0.76 | RXRA (0.41) | RXRARXRBRXRGESR1ESR2 | |
| SCHEMBL8678472 | 0.74 | ALDH1A1 (0.46) | RXRARXRBRXRGESR1ESR2 | |
| SCHEMBL22477463 | 0.74 | ALDH1A1 (0.46) | RXRARXRBRXRGESR1ESR2 | |
| SCHEMBL21730005 | 0.71 | RXRA (0.44) | RXRARXRBRXRGPRKCDKDM4E | |
| SCHEMBL6785200 | 0.71 | MAPT (0.46) | RXRAKDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306529-B1 | PERFUME COMPOSITION | TAKASAGO PERFUMERY CO. LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-4885274-A | ACYL-HEXAHYDRO-1H-CYCLOPENTA(A)NAPHTHALENE;MUSKS | TAKASAGO PERFUMERY CO., LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0306529-A1 | PERFUME COMPOSITION | TAKASAGO PERFUMERY CO. LTD. (JP) | 1989-03-15 | — | — | EP | disclosed |