Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84280 | 0.77 | ALDH1A1 (0.41) | TAAR1KMT2AALDH1A1NPC1MAPK1 | |
| Fluoride SCHEMBL28515671 | 0.75 | ALDH1A1 (0.40) | KMT2AALDH1A1NPC1MAPK1RAB9A | |
| SCHEMBL10628449 | 0.75 | ALDH1A1 (0.40) | PYCR1TAAR1KMT2AALDH1A1HTT | |
| SCHEMBL27459264 | 0.71 | ALDH1A1 (0.37) | KMT2AALDH1A1NPC1MAPK1RAB9A | |
| SCHEMBL16715934 | 0.70 | BCHE (0.54) | PYCR1TAAR1BCHEKMT2AACHE | |
| SCHEMBL6826572 | 0.69 | OPRM1 (0.39) | KMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5319401 | 0.69 | RAB9A (0.38) | BCHEKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL12124968 | 0.69 | PYCR1 (0.65) | PYCR1TAAR1BCHEACHEAOC3 | |
| SCHEMBL16335851 | 0.68 | SLC29A1 (0.36) | KMT2AALDH1A1NPC1MAPK1RAB9A | |
| SCHEMBL11010639 | 0.68 | S1PR1 (0.46) | PYCR1TAAR1BCHENAMPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321349-B1 | PROCESS FOR THE PREPARATION OF N-(2-CHLORO-BENZYL)(2-THIENYL)-2-ETHYL AMINE | ELF SANOFI (FR) | 1992-04-15 | — | — | EP | disclosed |
| EP-0321349-A1 | Process for the preparation of N-(2-chloro-benzyl)(2-thienyl)-2-ethyl amine | ELF SANOFI (FR) | 1989-06-21 | — | — | EP | disclosed |