Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305974 | 0.88 | PRMT1 (0.59) | PRMT1NR1H3KMT2AMEN1ALDH1A1 | |
| SCHEMBL9305975 | 0.88 | PRMT1 (0.59) | PRMT1NR1H3KMT2AMEN1ALDH1A1 | |
| SCHEMBL7754070 | 0.79 | ALDH1A1 (0.42) | NR1H3ALDH1A1NPC1 | |
| SCHEMBL8646877 | 0.78 | PRMT1 (0.51) | PRMT1NR1H3CYP1A2CYP2C9KMT2A | |
| SCHEMBL10981903 | 0.73 | CYP1A2 (0.57) | CYP1A2CYP2C9ALDH1A1MAPTRECQL | |
| SCHEMBL7927174 | 0.73 | CYP1A2 (0.57) | CYP1A2CYP2C9ALDH1A1MAPTRECQL | |
| SCHEMBL9781414 | 0.72 | NPC1 (0.60) | NR1H3KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9871954 | 0.72 | TYMS (0.58) | CYP1A2CYP2C9KMT2AMEN1ALDH1A1 | |
| SCHEMBL10473021 | 0.71 | ALOX5 (0.57) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL1556592 | 0.70 | CYP1A2 (0.76) | CYP1A2CYP2C9KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358108-B1 | 5-(N-3,4,5,6-TETRAHYDROPHTHALIMIDO)-CINNAMIC-ACID DERIVATIVES | BASF AG (DE) | 1992-04-15 | — | — | EP | claimed |