SCHEMBL9629170

SCHEMBL9629170

[CH2]C(Cc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
SLC6A2 P23975 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
ATM Q13315 1/20 0.44
KIF11 P52732 1/20 0.42
LMNA P02545 1/20 0.41
CYP2D6 P10635 1/20 0.41
KCNA5 P22460 1/20 0.41
HIF1A Q16665 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CALM1 P0DP23 1/20 0.39
FDPS P14324 1/20 0.39
CYP3A4 P08684 2/20 0.37
EPHX1 P07099 1/20 0.37
RECQL P46063 1/20 0.37
TRPA1 O75762 1/20 0.36
IDO1 P14902 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6985798 0.88 KIF11 (0.51) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL11243739 0.76 DRD2 (0.43) CYP1A2CYP2C9CYP2C19TAAR1ATM
SCHEMBL5371388 0.76 SLC6A2 (0.50) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL11860744 0.74 CYP1A2 (0.58) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL5946723 0.74 CYP1A2 (0.58) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL126749 0.74 CYP2C9 (0.58) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL9063882 0.74 CYP1A2 (0.58) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL5968241 0.72 CYP1A2 (0.56) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL2376206 0.72 SLC6A2 (0.46) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL9320828 0.72 CYP1A2 (0.56) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0145654-B2 METHOD OF LINING THE INSIDES OF PIPES OR PARTS OF PIPES CIBA-GEIGY AG (CH) 1992-05-13 EP claimed