SCHEMBL2834207

SCHEMBL2834207

C=CCc1ccc2c(c1O)C(=O)c1ccccc1C2=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 10/20 0.67
MAPT P10636 5/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
MCL1 Q07820 3/20 0.56
ALDH1A1 P00352 3/20 0.56
BCL2 P10415 2/20 0.56
MAPK1 P28482 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
KDM4E B2RXH2 1/20 0.56
CYP3A4 P08684 1/20 0.56
HPGD P15428 1/20 0.56
ALOX15 P16050 1/20 0.56
ALOX12 P18054 1/20 0.56
MAOA P21397 1/20 0.56
APEX1 P27695 1/20 0.56
RECQL P46063 1/20 0.56
DAPK1 P53355 1/20 0.56
CYP1B1 Q16678 1/20 0.56
HSD17B10 Q99714 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30497048 1.00 ELANE (0.67) ELANEMAPTMEN1KMT2AMCL1
SCHEMBL5919605 0.92 ELANE (0.63) ELANEMAPTMEN1KMT2AMCL1
SCHEMBL9629402 0.90 ELANE (0.70) ELANEMAPTMEN1KMT2AMCL1
SCHEMBL7600157 0.83 ELANE (0.48) ELANEMAPTMEN1KMT2AMCL1
SCHEMBL11412142 0.81 GABRA1 (0.46) ELANEMAPTMEN1KMT2AALDH1A1
SCHEMBL9282673 0.81 MAOA (0.56) ELANEMAPTMEN1KMT2AMCL1
SCHEMBL16225888 0.81 ELANE (1.00) ELANEMAPTMEN1KMT2AGABRA1
SCHEMBL7623901 0.81 ELANE (0.57) ELANEMAPTMEN1KMT2AMCL1
SCHEMBL4349729 0.81 ELANE (0.47) ELANEMAPTMEN1KMT2AMCL1
SCHEMBL7623905 0.81 ELANE (0.57) ELANEMAPTMEN1KMT2AMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023143608-A1 COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF 上海复东生物医药有限责任公司 2023-08-03 WO claimed
CN-116510024-A Composition, preparation method and application thereof 上海复东生物医药有限责任公司 2023-08-01 CN claimed
WO-2023068423-A1 COMPLEX ANTICANCER DRUG COMPOSITION USING PHOTOREACTIVITY AND PREPARATION METHOD THEREFOR 닥터아이앤비(주) 2023-04-27 WO claimed
CN-110693863-A Application of pharmaceutical composition in preparation of medicine for treating acute myeloid leukemia 浙江大学 2020-01-17 CN claimed
US-9801898-B2 Glutamate dehydrogenase 1 inhibitors and methods of treating cancer EMORY UNIVERSITY 2017-10-31 US claimed
US-20160228466-A1 Glutamate Dehydrogenase 1 Inhibitors and Methods of Treating Cancer NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-08-11 US claimed
EP-4653523-A1 CULTURE MEDIUM, PRODUCTION METHOD, AND CELL PREPARATION National University Corporation Kumamoto University (JP) 2025-11-26 EP disclosed
WO-2024154828-A1 CULTURE MEDIUM, PRODUCTION METHOD, AND CELL PREPARATION 国立大学法人熊本大学 2024-07-25 WO disclosed
WO-2023143608-A1 COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF 上海复东生物医药有限责任公司 2023-08-03 WO disclosed
CN-116510024-A Composition, preparation method and application thereof 上海复东生物医药有限责任公司 2023-08-01 CN disclosed
WO-2023068423-A1 COMPLEX ANTICANCER DRUG COMPOSITION USING PHOTOREACTIVITY AND PREPARATION METHOD THEREFOR 닥터아이앤비(주) 2023-04-27 WO disclosed
US-20200188431-A1 GLUTAMINE DEHYDROGENASE INHIBITORS FOR USE IN MUSCLE REGENERATION KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2020-06-18 US disclosed
CN-110693863-A Application of pharmaceutical composition in preparation of medicine for treating acute myeloid leukemia 浙江大学 2020-01-17 CN disclosed
US-20140042026-A1 ELECTROCHEMICAL SENSORS SENSOR INNOVATIONS, INC. (US) 2014-02-13 US disclosed
US-20130248364-A1 ELECTROCHEMICAL SENSORS SENSOR INNOVATIONS 2013-09-26 US disclosed
US-20120187000-A1 ELECTROCHEMICAL SENSORS Sensor Innovation, Inc. A Delaware Corporation (US) 2012-07-26 US disclosed
WO-2012083258-A2 ELECTROCHEMICAL SENSORS SENSOR INNOVATIONS, INC. (US) 2012-06-21 WO disclosed
CN-101765766-A Semiconductor electrochemical sensor SENSOR INNOVATIONS INC 2010-06-30 CN disclosed
EP-2171440-A1 SEMICONDUCTOR ELECTROCHEMICAL SENSORS Sensor Innovations Inc. (US) 2010-04-07 EP disclosed
WO-2008154409-A1 SEMICONDUCTOR ELECTROCHEMICAL SENSORS SENSOR INNOVATIONS INC. (US) 2008-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200188431-A1 GLUTAMINE DEHYDROGENASE INHIBITORS FOR USE IN MUSCLE REGENERATION GLUL, GLS2, GLS ELANE 2473/4885MAPT 4363/4885MEN1 4556/4885
US-20160228466-A1 Glutamate Dehydrogenase 1 Inhibitors and Methods of Treating Cancer ALDH7A1, ALDH1A1, DPYD ELANE 1635/4885MAPT 4069/4885MEN1 2249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.