Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632286 | 1.00 | MAOB (0.53) | MAOBPOLBALOX5EPHX2MAOA | |
| SCHEMBL3499767 | 0.85 | MAOB (0.58) | MAOBALOX5EPHX2 | |
| SCHEMBL68570 | 0.83 | ALOX5 (0.69) | MAOBALOX5ALDH1A1RAB9APARP10 | |
| SCHEMBL48403 | 0.82 | CYP19A1 (0.50) | POLBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL1928563 | 0.82 | MAOB (0.71) | MAOBPOLBMAOAALDH1A1MAPT | |
| SCHEMBL6959187 | 0.82 | MAOB (0.71) | MAOBMAOAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9630106 | 0.82 | ACACB (0.58) | ALOX5RAB9AHTTSMN1; SMN2 | |
| SCHEMBL16866569 | 0.81 | POLB (0.54) | POLBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL4186 | 0.81 | MAOB (0.74) | MAOB | |
| Ethylene SCHEMBL11248134 | 0.81 | ALOX5 (0.66) | MAOBALOX5ALDH1A1RAB9APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153210-A | Hypoglycemic agent, animal growth regulator; veterinary medicine | BEECHAM GROUP P.L.C. (GB) | 1992-10-06 | — | — | US | disclosed |
| EP-0236624-A2 | Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-09-16 | — | — | EP | disclosed |