Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14676052 | 0.87 | NAPRT (0.66) | ACACBCYP19A1CYP11B1CYP11B2MAPK1 | |
| SCHEMBL15753209 | 0.86 | RAB9A (0.66) | ACACBCYP19A1CYP11B1CYP11B2MAPK1 | |
| SCHEMBL5830825 | 0.86 | ACACB (0.53) | ACACBCYP19A1CYP11B1CYP11B2MAPK1 | |
| SCHEMBL6955979 | 0.84 | MAOB (0.68) | ACACBCYP19A1CYP11B1CYP11B2MAPK1 | |
| SCHEMBL28048524 | 0.83 | MAPK1 (0.64) | ACACBCYP19A1CYP11B1CYP11B2MAPK1 | |
| SCHEMBL9632286 | 0.82 | MAOB (0.53) | SMN1; SMN2HTTRAB9AALOX5 | |
| SCHEMBL9630186 | 0.82 | MAOB (0.53) | SMN1; SMN2HTTRAB9AALOX5 | |
| SCHEMBL68570 | 0.82 | ALOX5 (0.69) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| SCHEMBL29611658 | 0.81 | NAPRT (0.69) | CYP19A1KMT2ARECQLCYP1A2CYP3A4 | |
| SCHEMBL48669 | 0.81 | NAPRT (0.69) | CYP19A1KMT2ARECQLCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153210-A | Hypoglycemic agent, animal growth regulator; veterinary medicine | BEECHAM GROUP P.L.C. (GB) | 1992-10-06 | — | — | US | disclosed |
| EP-0236624-A2 | Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-09-16 | — | — | EP | disclosed |