Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499146 | 0.94 | HRH3 (0.42) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL28205449 | 0.82 | SLC6A3 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24688643 | 0.78 | HRH3 (0.40) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL9370536 | 0.78 | HRH3 (0.40) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL3160023 | 0.78 | HRH3 (0.40) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL22363315 | 0.77 | HRH3 (0.39) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL21210881 | 0.77 | HRH3 (0.39) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL24604493 | 0.77 | OPRM1 (0.39) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL22446838 | 0.77 | HRH3 (0.39) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL22877461 | 0.77 | HRH3 (0.42) | HRH3MAPTALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220112-B1 | AROMATIC DERIVATIVES SUBSTITUTED BY AN (OMEGA-AMINO)-ALKANOL GROUP WITH AN ANTIMICROBIAL ACTIVITY, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | ELF SANOFI (FR) | 1992-04-08 | — | — | EP | disclosed |
| EP-0220112-A2 | Aromatic derivatives substituted by an (omega-amino)-alkanol group with an antimicrobial activity, their preparation and compositions containing them | ELF SANOFI (FR) | 1987-04-29 | — | — | EP | disclosed |