SCHEMBL28205449

SCHEMBL28205449

CCCC(Cl)N1CCCC1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 18/20 0.37
SLC6A2 P23975 15/20 0.37
SLC6A4 P31645 11/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10499146 0.84 HRH3 (0.42) SLC6A3SLC6A2SLC6A4
SCHEMBL9630262 0.82 HRH3 (0.38) SLC6A3SLC6A2SLC6A4
SCHEMBL7678645 0.81 SIGMAR1 (0.36) SLC6A3SLC6A2SLC6A4
SCHEMBL4691097 0.79
SCHEMBL10419521 0.79
SCHEMBL4294178 0.77 SLC6A3 (0.35) SLC6A3SLC6A2SLC6A4
Hydrochloric Acid SCHEMBL4931478 0.77 SLC6A3 (0.35) SLC6A3SLC6A2SLC6A4
Hydrochloric Acid SCHEMBL1622048 0.75 SLC6A4 (0.34) SLC6A3SLC6A2SLC6A4
SCHEMBL898138 0.74 SLC6A3 (0.39) SLC6A3SLC6A2SLC6A4
SCHEMBL5709265 0.74 SLC6A3 (0.39) SLC6A3SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107698539-A The preparation method of Buflomedil Hydrochloride 陕西启源科技发展有限责任公司 2018-02-16 CN claimed
CN-107698539-A The preparation method of Buflomedil Hydrochloride 陕西启源科技发展有限责任公司 2018-02-16 CN disclosed