Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TERT | O14746 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629545 | 0.96 | SMN1; SMN2 (0.65) | ALDH1A1HTTMEN1POLBKMT2A | |
| SCHEMBL4297878 | 0.87 | TERT (0.75) | ALDH1A1HTTMEN1POLBKMT2A | |
| SCHEMBL9630665 | 0.87 | TERT (0.79) | ALDH1A1HTTATMLMNAHPGD | |
| SCHEMBL4299285 | 0.86 | TERT (0.76) | ALDH1A1POLBGAASMN1; SMN2HPGD | |
| SCHEMBL9630688 | 0.84 | TERT (0.74) | ALDH1A1MEN1POLBKMT2AGAA | |
| SCHEMBL4289287 | 0.84 | TERT (0.74) | ALDH1A1MEN1POLBKMT2AGAA | |
| SCHEMBL4291737 | 0.84 | TERT (0.59) | ALDH1A1TERT | |
| SCHEMBL9921691 | 0.79 | ATM (0.76) | ALDH1A1HTTATMLMNASMN1; SMN2 | |
| SCHEMBL11732314 | 0.77 | TERT (0.78) | ALDH1A1HTTMEN1POLBKMT2A | |
| SCHEMBL13597049 | 0.77 | ALDH1A1 (0.77) | ALDH1A1HTTMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482119-A1 | INTERCALATING AGENTS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1992-04-29 | — | — | EP | claimed |
| WO-1991000265-A1 | INTERCALATING AGENTS | CANCER RESEARCH TECHNOLOGY LTD. (GB) | 1991-01-10 | — | — | WO | claimed |