Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 13/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289287 | 1.00 | TERT (0.74) | TERTALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL21085334 | 0.89 | TERT (0.63) | TERTALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL4293444 | 0.88 | TERT (0.95) | TERTALDH1A1MAPTLMNA | |
| SCHEMBL4297878 | 0.87 | TERT (0.75) | TERTALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL4299285 | 0.86 | TERT (0.76) | TERTALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL4291737 | 0.84 | TERT (0.59) | TERTALDH1A1MAPT | |
| SCHEMBL9630438 | 0.84 | ALDH1A1 (0.64) | TERTALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL9629545 | 0.81 | SMN1; SMN2 (0.65) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL8288400 | 0.80 | LMNA (0.68) | ALDH1A1SMN1; SMN2LMNAGAAATM | |
| SCHEMBL31559143 | 0.79 | GAA (0.67) | ALDH1A1MAPTSMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482119-A1 | INTERCALATING AGENTS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1992-04-29 | — | — | EP | claimed |
| WO-1991000265-A1 | INTERCALATING AGENTS | CANCER RESEARCH TECHNOLOGY LTD. (GB) | 1991-01-10 | — | — | WO | claimed |