Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | TTPA | P49638 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125937 | 0.89 | MEN1 (0.36) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9632161 | 0.86 | TTPA (0.39) | MEN1KMT2ATTPAALDH1A1 | |
| SCHEMBL9632167 | 0.85 | MEN1 (0.34) | MEN1KMT2APDE4APDE3A | |
| SCHEMBL9630971 | 0.82 | PPARG (0.31) | MEN1KMT2APDE4APDE3AKDM4E | |
| SCHEMBL9631349 | 0.80 | MEN1 (0.47) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8177483 | 0.77 | KMT2A (0.39) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL7487350 | 0.76 | MEN1 (0.52) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL10640049 | 0.75 | MEN1 (0.42) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL10641941 | 0.73 | PPARG (0.39) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL10641768 | 0.73 | MEN1 (0.46) | MEN1KMT2APDE4APDE3ATTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |