Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | TTPA | P49638 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641737 | 0.89 | MAPT (0.47) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL9631986 | 0.88 | TTPA (0.46) | MAPTMEN1KMT2APSEN1MGLL | |
| SCHEMBL9632130 | 0.87 | PSEN1 (0.44) | MAPTMEN1KMT2ATDP1PSEN1 | |
| SCHEMBL10638977 | 0.84 | MAPT (0.45) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL9632107 | 0.82 | MAPT (0.60) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL9630933 | 0.79 | MEN1 (0.47) | MAPTMEN1KMT2ATDP1PSEN1 | |
| SCHEMBL9075115 | 0.78 | MAPT (0.49) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL10636475 | 0.77 | MEN1 (0.48) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL10636293 | 0.76 | TTPA (0.49) | MAPTMEN1KMT2ATDP1PSEN1 | |
| SCHEMBL9631318 | 0.75 | PSEN1 (0.46) | MAPTMEN1KMT2ATDP1PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |