Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TTPA | P49638 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630744 | 0.88 | MEN1 (0.46) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL9632167 | 0.88 | MEN1 (0.34) | KMT2AMEN1PDE4APDE3A | |
| SCHEMBL9632039 | 0.87 | NPC1 (0.36) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL9632315 | 0.87 | KMT2A (0.42) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL8177483 | 0.86 | KMT2A (0.39) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL9632161 | 0.86 | TTPA (0.39) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL10642037 | 0.84 | TTPA (0.47) | KMT2AMEN1MAPTMAOBTTPA | |
| SCHEMBL9632313 | 0.81 | MEN1 (0.30) | KMT2AMEN1PDE4APDE3A | |
| SCHEMBL10636293 | 0.76 | TTPA (0.49) | KMT2AMEN1MAPTMAOBTTPA | |
| SCHEMBL9630952 | 0.76 | TTPA (0.41) | KMT2ANPC1RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |