Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | RASGRP3 | Q8IV61 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631440 | 0.87 | KMT2A (0.38) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL9632315 | 0.86 | KMT2A (0.42) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL9630744 | 0.76 | MEN1 (0.46) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL9630952 | 0.73 | TTPA (0.41) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL9531639 | 0.73 | KMT2A (0.42) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL10639032 | 0.72 | KMT2A (0.47) | KMT2AMEN1MAPT | |
| SCHEMBL9632161 | 0.72 | TTPA (0.39) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL8177483 | 0.72 | KMT2A (0.39) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL9632130 | 0.72 | PSEN1 (0.44) | KMT2AMEN1MAPT | |
| SCHEMBL10642037 | 0.71 | TTPA (0.47) | KMT2AMEN1MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |