SCHEMBL9632634

SCHEMBL9632634

CC1CN(CCC[Si](C)(C)c2ccccc2)CC(C)O1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
ALDH1A1 P00352 4/20 0.50
TDP1 Q9NUW8 1/20 0.50
MGAM O43451 1/20 0.49
LMNA P02545 1/20 0.48
POLB P06746 2/20 0.47
SIGMAR1 Q99720 3/20 0.46
EBP Q15125 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
GAA P10253 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HTT P42858 2/20 0.43
DRD2 P14416 1/20 0.43
HTR2A P28223 1/20 0.43
BLM P54132 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9631487 0.88 ALDH1A1 (0.55) KDM4EALDH1A1TDP1MGAMLMNA
SCHEMBL9631471 0.85 ALDH1A1 (0.52) KDM4EALDH1A1TDP1LMNAPOLB
SCHEMBL9632652 0.83 SIGMAR1 (0.65) KDM4EALDH1A1TDP1LMNASIGMAR1
SCHEMBL9631903 0.83 KDM4E (0.47) KDM4EALDH1A1TDP1LMNASIGMAR1
SCHEMBL9631817 0.81 LMNA (0.44) KDM4EALDH1A1TDP1LMNASIGMAR1
SCHEMBL9631134 0.79 SIGMAR1 (0.51) KDM4EALDH1A1TDP1LMNASIGMAR1
SCHEMBL9663923 0.78 SIGMAR1 (0.49) KDM4EALDH1A1TDP1LMNASIGMAR1
SCHEMBL9631442 0.72 KDM4E (0.60) KDM4EALDH1A1TDP1LMNAPOLB
SCHEMBL18084487 0.72 MGAM (0.44) MGAMLMNA
SCHEMBL13305355 0.72 SIGMAR1 (0.63) KDM4EALDH1A1TDP1LMNASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0313353-B1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI DOWELANCO (US) 1992-06-17 EP claimed
US-4927812-A FUNGICIDES ATOCHEM NORTH AMERICA, INC. (US) 1990-05-22 US claimed
WO-1989003640-A1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI THE DOW CHEMICAL COMPANY (US) 1989-05-05 WO claimed
EP-0313353-A1 Morpholinyl silanes and use for control of plant diseases caused by fungi DOWELANCO (US) 1989-04-26 EP claimed
EP-0313353-B1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI DOWELANCO (US) 1992-06-17 EP disclosed
EP-0313353-A1 Morpholinyl silanes and use for control of plant diseases caused by fungi DOWELANCO (US) 1989-04-26 EP disclosed