Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743771 | 0.80 | KEAP1 (0.53) | MAPTKEAP1HPGDL3MBTL1LMNA | |
| SCHEMBL6844310 | 0.80 | KEAP1 (0.53) | MAPTHDAC3HDAC1KEAP1HPGD | |
| Benzene SCHEMBL27083018 | 0.79 | FOLH1 (0.55) | MAPTHPGDGAAKMT2AHTT | |
| SCHEMBL89060 | 0.79 | FOLH1 (0.55) | MAPTHPGDGAAKMT2AHTT | |
| SCHEMBL11668031 | 0.79 | BCAT2 (0.64) | MAPTHDAC3HDAC1HPGDLMNA | |
| SCHEMBL31448014 | 0.79 | KEAP1 (0.62) | MAPTKEAP1GAAEGLN1KMT2A | |
| SCHEMBL16566821 | 0.79 | KEAP1 (0.51) | MAPTKEAP1HPGDL3MBTL1LMNA | |
| SCHEMBL1276161 | 0.79 | KEAP1 (0.51) | MAPTKEAP1HPGDL3MBTL1LMNA | |
| SCHEMBL9743474 | 0.79 | KEAP1 (0.51) | MAPTKEAP1HPGDL3MBTL1LMNA | |
| SCHEMBL9356378 | 0.79 | KDM4E (0.44) | MAPTHDAC3HDAC1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082588-A | Hygrometers | ELLIOTT STANLEY B (US) | 1992-01-21 | — | — | US | claimed |