Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 6/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646458 | 0.91 | CHRM1 (0.50) | LMNATRPA1CHRM1ADRA1ASLC6A2 | |
| SCHEMBL5163687 | 0.88 | CHRM1 (0.43) | LMNATRPA1CHRM1ADRA1ASLC6A2 | |
| SCHEMBL6939529 | 0.82 | RORC (0.59) | LMNATRPA1CHRM1ADRA1ASLC6A2 | |
| SCHEMBL7944724 | 0.82 | CHRM1 (0.48) | LMNATRPA1CHRM1ADRA1ASLC6A2 | |
| SCHEMBL11778568 | 0.78 | SRC (0.47) | LMNATRPA1CHRM1ADRA1ASLC6A2 | |
| SCHEMBL4784165 | 0.77 | ESR1 (0.68) | ADRA1ASLC6A2ESR1HSD17B10ESR2 | |
| SCHEMBL5699143 | 0.76 | TRPA1 (0.47) | LMNATRPA1CHRM1ADRA1ASLC6A2 | |
| Isothymol SCHEMBL852892 | 0.76 | LMNA (0.68) | LMNATRPA1CHRM1ADRA1ASLC6A2 | |
| SCHEMBL50784 | 0.76 | LMNA (0.56) | LMNATRPA1CHRM1ADRA1ASLC6A2 | |
| SCHEMBL28439539 | 0.76 | ESR1 (0.60) | LMNACHRM1ADRA1ASLC6A2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485472-A1 | BIS-CYCLIC PHOSPHITE COMPOUNDS AND POLYMERIC MATERIALS STABILIZED THEREWITH | EASTMAN KODAK COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| WO-1991001987-A1 | BIS-CYCLIC PHOSPHITE COMPOUNDS AND POLYMERIC MATERIALS STABILIZED THEREWITH | EASTMAN KODAK COMPANY (US) | 1991-02-21 | — | — | WO | disclosed |
| EP-0412028-A1 | Bis-cyclic phosphite compounds and polymeric materials stabilized therewith | EASTMAN KODAK COMPANY (US) | 1991-02-06 | — | — | EP | disclosed |
| US-4956406-A | Oxidation resistance of polypropylene or copolymers also heat resistance and radiation resistance | EASTMAN KODAK COMPANY (US) | 1990-09-11 | — | — | US | disclosed |