Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632900 | 0.83 | CA12 (0.48) | ALDH1A1PKMPOLBMAPTCYP1A2 | |
| SCHEMBL9632885 | 0.81 | MAPT (0.49) | ALDH1A1PKMGAAMEN1KMT2A | |
| SCHEMBL27685761 | 0.78 | ALDH1A1 (0.58) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL9633696 | 0.76 | SMN1; SMN2 (0.60) | ALDH1A1PKMGAAL3MBTL1POLB | |
| SCHEMBL17577750 | 0.75 | TAS1R3 (0.48) | ALDH1A1MEN1KMT2ATSHRPOLB | |
| SCHEMBL10725628 | 0.74 | CREBBP (0.62) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL10725513 | 0.74 | MAPT (0.54) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL9632487 | 0.74 | L3MBTL1 (0.62) | ALDH1A1PKML3MBTL1POLBMAPT | |
| SCHEMBL9633753 | 0.73 | ADRA1D (0.41) | ALDH1A1PKMGAAL3MBTL1MEN1 | |
| SCHEMBL9632001 | 0.72 | ATM (0.43) | PKMMEN1KMT2ATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331943-B1 | PHENOXYETHYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND COMPOSITION FOR EXHIBITING EXCELLENT ALPHA-1-BLOCKING ACTIVITY CONTAINING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-4971990-A | HYPOTENSIVE AGENTS, DYSUREA | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0331943-A1 | Phenoxyethylamine derivatives, process for preparing the same, and composition for exhibiting excellent alpha-1-blocking activity containing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1989-09-13 | — | — | EP | disclosed |