SCHEMBL9632648

SCHEMBL9632648

CC1CN(CCC(C)(C)[SiH2]c2ccc(C(C)(C)C)cc2)CC(C)O1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.58
EBP Q15125 2/20 0.49
ALDH1A1 P00352 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ADORA3 P0DMS8 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD3 P35462 1/20 0.38
KCNH2 Q12809 1/20 0.38
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM4E B2RXH2 2/20 0.34
HTT P42858 1/20 0.34
LMNA P02545 1/20 0.34
USP2 O75604 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9631467 0.86 KMT2A (0.44) SIGMAR1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL9631900 0.84 L3MBTL1 (0.45) SIGMAR1ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL9631481 0.81 ALDH1A1 (0.47) SIGMAR1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL9631130 0.81 KMT2A (0.46) SIGMAR1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL9631813 0.78 SMN1; SMN2 (0.45) SIGMAR1EBPALDH1A1KMT2AKDM4E
SCHEMBL19000986 0.72 SIGMAR1 (0.60) SIGMAR1EBPALDH1A1HSD17B10ADORA3
SCHEMBL19001047 0.72 SIGMAR1 (0.60) SIGMAR1EBPALDH1A1HSD17B10ADORA3
SCHEMBL11099523 0.72 SIGMAR1 (0.68) SIGMAR1EBPADORA3CHRM1DRD3
SCHEMBL9632652 0.70 SIGMAR1 (0.65) SIGMAR1EBPALDH1A1HSD17B10ADORA3
SCHEMBL17886531 0.69 SIGMAR1 (0.52) SIGMAR1EBPALDH1A1ADORA3CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1989003640-A1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI THE DOW CHEMICAL COMPANY (US) 1989-05-05 WO claimed
EP-0313353-B1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI DOWELANCO (US) 1992-06-17 EP disclosed
WO-1989003640-A1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI THE DOW CHEMICAL COMPANY (US) 1989-05-05 WO disclosed
EP-0313353-A1 Morpholinyl silanes and use for control of plant diseases caused by fungi DOWELANCO (US) 1989-04-26 EP disclosed