SCHEMBL9632652

SCHEMBL9632652

CC1CN(CCC[Si](C)(C)c2ccc(C(C)(C)C)cc2)CC(C)O1

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.65
EBP Q15125 2/20 0.49
KDM4E B2RXH2 4/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 1/20 0.39
ADORA3 P0DMS8 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD3 P35462 1/20 0.38
KCNH2 Q12809 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KMT2A Q03164 1/20 0.37
HTT P42858 1/20 0.37
TSHR P16473 1/20 0.37
ATM Q13315 1/20 0.37
NR1H2 P55055 2/20 0.37
NR1H3 Q13133 2/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9663923 0.84 SIGMAR1 (0.49) SIGMAR1EBPKDM4ELMNAALDH1A1
SCHEMBL9631471 0.83 ALDH1A1 (0.52) SIGMAR1EBPKDM4ELMNAALDH1A1
SCHEMBL9632634 0.83 KDM4E (0.50) SIGMAR1EBPKDM4ELMNAALDH1A1
SCHEMBL9631903 0.81 KDM4E (0.47) SIGMAR1EBPKDM4ELMNAALDH1A1
SCHEMBL9631817 0.79 LMNA (0.44) SIGMAR1EBPKDM4ELMNAALDH1A1
SCHEMBL9631487 0.78 ALDH1A1 (0.55) SIGMAR1KDM4ELMNAALDH1A1TDP1
SCHEMBL9631134 0.77 SIGMAR1 (0.51) SIGMAR1EBPKDM4ELMNAALDH1A1
SCHEMBL19000986 0.72 SIGMAR1 (0.60) SIGMAR1EBPALDH1A1HSD17B10ADORA3
SCHEMBL19001047 0.72 SIGMAR1 (0.60) SIGMAR1EBPALDH1A1HSD17B10ADORA3
SCHEMBL11099523 0.72 SIGMAR1 (0.68) SIGMAR1EBPKDM4ELMNAADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4927812-A FUNGICIDES ATOCHEM NORTH AMERICA, INC. (US) 1990-05-22 US claimed
WO-1989003640-A1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI THE DOW CHEMICAL COMPANY (US) 1989-05-05 WO claimed
EP-0313353-B1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI DOWELANCO (US) 1992-06-17 EP disclosed
US-4927812-A FUNGICIDES ATOCHEM NORTH AMERICA, INC. (US) 1990-05-22 US disclosed
WO-1989003640-A1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI THE DOW CHEMICAL COMPANY (US) 1989-05-05 WO disclosed
EP-0313353-A1 Morpholinyl silanes and use for control of plant diseases caused by fungi DOWELANCO (US) 1989-04-26 EP disclosed