Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.54 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209829 | 0.85 | SLC6A5 (0.59) | FAAHMEN1KMT2AMAPK1NOD1 | |
| SCHEMBL7215978 | 0.85 | SLC6A5 (0.59) | FAAHMEN1KMT2AMAPK1NOD1 | |
| SCHEMBL15313039 | 0.85 | PLA2G2C (0.60) | FAAHMEN1KMT2AMAPK1PLA2G2C | |
| SCHEMBL7215943 | 0.85 | SLC6A5 (0.59) | FAAHMEN1KMT2AMAPK1NOD1 | |
| SCHEMBL27736241 | 0.84 | MEN1 (0.52) | FAAHMEN1KMT2AMAPK1NOD1 | |
| SCHEMBL6808296 | 0.83 | NOD1 (0.72) | FAAHMEN1KMT2AMAPK1NOD1 | |
| SCHEMBL117117 | 0.82 | FAAH (0.63) | FAAHMEN1KMT2AMAPK1NOD1 | |
| SCHEMBL115769 | 0.82 | FAAH (0.63) | FAAHMEN1KMT2AMAPK1NOD1 | |
| SCHEMBL115687 | 0.82 | FAAH (0.63) | FAAHMEN1KMT2AMAPK1NOD1 | |
| SCHEMBL248586 | 0.82 | FAAH (0.63) | FAAHMEN1KMT2AMAPK1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |