Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209829 | 1.00 | SLC6A5 (0.59) | SLC6A5DNM1FAAHMEN1KMT2A | |
| SCHEMBL7215943 | 1.00 | SLC6A5 (0.59) | SLC6A5DNM1FAAHMEN1KMT2A | |
| SCHEMBL11405576 | 0.92 | SLC6A5 (0.48) | SLC6A5DNM1FAAHMEN1KMT2A | |
| SCHEMBL15313039 | 0.87 | PLA2G2C (0.60) | FAAHMEN1KMT2AMAPK1PLA2G2C | |
| SCHEMBL27736241 | 0.86 | MEN1 (0.52) | SLC6A5DNM1FAAHMEN1KMT2A | |
| SCHEMBL5494620 | 0.86 | GSR (0.45) | SLC6A5DNM1MEN1KMT2AGNAI3 | |
| SCHEMBL8013202 | 0.85 | LMNA (0.57) | SLC6A5MEN1KMT2APLA2G2CPLA2G10 | |
| SCHEMBL25417289 | 0.85 | DNM1 (0.68) | SLC6A5DNM1FAAHMEN1KMT2A | |
| SCHEMBL9632841 | 0.85 | FAAH (0.56) | SLC6A5DNM1FAAHMEN1KMT2A | |
| SCHEMBL7208665 | 0.85 | SLC6A5 (0.60) | SLC6A5DNM1FAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920434-A3 | BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | F.HOFFMANN-LA ROCHE AG (CH) | 2003-06-04 | — | — | EP | disclosed |
| EP-0920434-B1 | BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | HOFFMANN LA ROCHE (CH) | 2002-10-16 | — | — | EP | disclosed |
| US-6060616-A | ANTITUMORS AGENTS; LEUKEMIA, OVARIAN CARCINOMA | HOFFMANN-LA ROCHE INC. (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0920434-A2 | BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | F.HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998003518-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-29 | — | — | WO | disclosed |