Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 15/20 | 0.38 |
| ▸ | PPARA | Q07869 | 13/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Medifoxamine SCHEMBL1649943 | 0.71 | LMNA (0.45) | MTNR1AMTNR1BCYP2C19NPC1RAB9A | |
| Medifoxamine SCHEMBL4416212 | 0.71 | LMNA (0.45) | MTNR1AMTNR1BCYP2C19NPC1RAB9A | |
| SCHEMBL1538040 | 0.71 | ALOX15 (0.48) | MTNR1AMTNR1BPPARGPPARAALOX15 | |
| Medifoxamine SCHEMBL49319 | 0.71 | HTR2A (0.50) | MTNR1AMTNR1BCYP2C19NPC1RAB9A | |
| SCHEMBL28444649 | 0.71 | MTNR1A (0.44) | MTNR1AMTNR1BPPARGPPARAALOX15 | |
| Medifoxamine SCHEMBL1171221 | 0.69 | HTR2A (0.48) | MTNR1AMTNR1BCYP2C19NPC1RAB9A | |
| SCHEMBL12537686 | 0.69 | MTNR1A (0.44) | MTNR1AMTNR1BPPARGPPARAALOX15 | |
| SCHEMBL8973243 | 0.68 | PPARG (0.45) | MTNR1AMTNR1BPPARGPPARAALOX15 | |
| SCHEMBL11279740 | 0.68 | SMN1; SMN2 (0.43) | MTNR1AMTNR1BPPARGPPARAALOX15 | |
| SCHEMBL9780112 | 0.68 | PPARG (0.42) | MTNR1AMTNR1BPPARGPPARAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2304057-A | — | — | None | — | — | JP | disclosed |
| US-5114968-A | Ovicides, pesticides | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | disclosed |
| JP-H02304057-A | ACYLATED CARBAMATE | CIBA GEIGY AG | 1990-12-17 | — | — | JP | disclosed |