Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632708 | 0.85 | GLA (0.40) | SMN1; SMN2NPC1RAB9AMAPK1GSK3B | |
| SCHEMBL10364612 | 0.85 | MAPT (0.56) | SMN1; SMN2NPC1RAB9AHPGDMAPK1 | |
| SCHEMBL10364759 | 0.84 | HTT (0.55) | SMN1; SMN2NPC1RAB9AMAPK1MAPT | |
| SCHEMBL10363894 | 0.84 | MAPT (0.60) | NPSR1SMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL10364618 | 0.82 | MAPT (0.53) | NPSR1SMN1; SMN2NPC1RAB9AGSK3B | |
| SCHEMBL17068793 | 0.80 | MAPT (0.74) | NPSR1SMN1; SMN2EGFRNPC1RAB9A | |
| SCHEMBL17068760 | 0.80 | NPSR1 (0.60) | NPSR1SMN1; SMN2EGFRNPC1RAB9A | |
| SCHEMBL9633100 | 0.80 | SMN1; SMN2 (0.41) | NPSR1SMN1; SMN2EGFRNPC1RAB9A | |
| SCHEMBL9631769 | 0.77 | PKM (0.42) | SMN1; SMN2NPC1RAB9AMAPTTHRB | |
| SCHEMBL7025544 | 0.77 | NPSR1 (0.56) | NPSR1SMN1; SMN2EGFRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162349-A | Mercaptobis/1,3,4-oxa- and -thiadiazoles/ | CIBA-GEIGY CORPORATION (US) | 1992-11-10 | — | — | US | claimed |
| EP-0364396-A1 | Neumaticides and fungicides | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | claimed |
| US-5162349-A | Mercaptobis/1,3,4-oxa- and -thiadiazoles/ | CIBA-GEIGY CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0364396-A1 | Neumaticides and fungicides | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | disclosed |