Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076641 | 0.84 | GSTO1 (0.57) | CYP3A4NPSR1NPC1RAB9ALMNA | |
| SCHEMBL10347962 | 0.83 | TSHR (0.55) | CYP3A4MAPTNPSR1NPC1RAB9A | |
| SCHEMBL9427381 | 0.81 | NPC1 (0.64) | CYP3A4MAPTNPSR1NPC1RAB9A | |
| SCHEMBL17603210 | 0.78 | EPHX1 (0.52) | CYP3A4MAPTNPC1RAB9AMEN1 | |
| SCHEMBL9391202 | 0.78 | GSTO1 (0.55) | CYP3A4RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9815484 | 0.77 | PKM (0.59) | CYP3A4MAPTNPC1RAB9AMEN1 | |
| SCHEMBL5692447 | 0.77 | NPC1 (0.57) | MAPTNPSR1NPC1RAB9AMEN1 | |
| SCHEMBL8876963 | 0.76 | KMT2A (0.63) | CYP3A4MAPTNPSR1NPC1RAB9A | |
| SCHEMBL9823940 | 0.76 | MEN1 (0.52) | MAPTNPSR1NPC1RAB9AMEN1 | |
| SCHEMBL8876305 | 0.76 | ALDH1A1 (0.58) | MAPTNPC1RAB9AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63310855-A | — | — | None | — | — | JP | disclosed |
| US-5084085-A | Plant growth regulators | FMC CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |
| US-4885025-A | A PHENOXY-,-AMINO-,-ALKYLAMINO- OR -SULFIDO-SUBSTITUTED PHENYL ON THE NUMBER 1 RING NITROGEN | FMC CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| US-4816065-A | ARYLTETRAHYDROPHTHALIMIDES | FMC CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| JP-S63310855-A | 5-(1-BUTYN-3-YL)OXY-4-CHLORO-2-FLUOROACETANILIDE AND PRODUCTION THEREOF | SUMITOMO CHEM CO LTD | 1988-12-19 | — | — | JP | disclosed |