Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MB | P02144 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198183 | 0.85 | HSD17B10 (0.59) | PKMSMN1; SMN2POLBALDH1A1MEN1 | |
| SCHEMBL5674663 | 0.85 | HSD17B10 (0.59) | PKMSMN1; SMN2POLBALDH1A1MEN1 | |
| SCHEMBL4548035 | 0.84 | EPHX1 (0.70) | PKMSMN1; SMN2POLBMEN1MAPT | |
| SCHEMBL17603210 | 0.82 | EPHX1 (0.52) | PKMPOLBALDH1A1MEN1MAPT | |
| SCHEMBL3192352 | 0.82 | PKM (0.65) | PKMSMN1; SMN2POLBALDH1A1MEN1 | |
| SCHEMBL19049142 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2POLBALDH1A1MEN1MAPT | |
| SCHEMBL405569 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2POLBALDH1A1KMT2ARORC | |
| SCHEMBL13602308 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5692447 | 0.81 | NPC1 (0.57) | PKMPOLBALDH1A1MEN1MAPT | |
| SCHEMBL3791892 | 0.81 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9954190-B2 | Organic electric-field light-emitting element, light-emitting material for organic electric-field light-emitting element, and light-emitting device, display device, and illumination device using same element | UDC IRELAND LIMITED (IE) | 2018-04-24 | — | — | US | disclosed |
| US-20170174658-A1 | PYRIDIN-2(1H)-ONE QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS | FORMA THERAPEUTICS, INC. | 2017-06-22 | — | — | US | disclosed |
| US-9412963-B2 | Organic electroluminescent element, material for organic electroluminescent element, and light emitting device, display device and illumination device each using the element | UDC IRELAND LIMITED (IE) | 2016-08-09 | — | — | US | disclosed |
| US-8877752-B2 | 4(1H)-quinolones having antimalarial activity with reduced chemical resistance | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-11-04 | — | — | US | disclosed |
| US-20140159024-A1 | Organic Electric-Field Light-Emitting Element, Light-Emitting Material For Organic Electric-Field Light-Emitting Element, And Light-Emitting Device, Display Device, And Illumination Device Using Same Element | UDC IRELAND LIMITED (IE) | 2014-06-12 | — | — | US | disclosed |
| US-20140159024-A1 | Organic Electric-Field Light-Emitting Element, Light-Emitting Material For Organic Electric-Field Light-Emitting Element, And Light-Emitting Device, Display Device, And Illumination Device Using Same Element | UDC IRELAND LIMITED (IE) | 2014-06-12 | — | — | US | disclosed |
| US-20130123258-A1 | 4(1H)-Quinolones Having Antimalarial Activity With Reduced Chemical Resistance | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-05-16 | — | — | US | disclosed |
| US-20130119359-A1 | Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element | UDC IRELAND LIMITED (IE) | 2013-05-16 | — | — | US | disclosed |
| EP-0205983-B1 | COLOR LIGHT-SENSITIVE MATERIALS | FUJI PHOTO FILM CO., LTD. (JP) | 1991-10-02 | — | — | EP | disclosed |
| US-4741997-A | Color light-sensitive materials with azo dyes | FUJI PHOTO FILM CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0205983-A2 | Color light-sensitive materials | FUJI PHOTO FILM CO., LTD. (JP) | 1986-12-30 | — | — | EP | disclosed |
| US-4473374-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1984-09-25 | — | — | US | disclosed |
| US-4330291-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-18 | — | — | US | disclosed |
| US-4248591-A | HAIR DYES | L'OREAL (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | disclosed |
| US-4093806-A | HAIR DYES | L'OREAL (FR) | 1978-06-06 | — | — | US | disclosed |
| US-4046786-A | HAIR DYES | L'OREAL (FR) | 1977-09-06 | — | — | US | disclosed |
| US-3977825-A | Indoanilines in keratinic fiber dye cmpositions | L'OREAL (FR) | 1976-08-31 | — | — | US | disclosed |
| US-3948596-A | Oxidation dye for keratinic fibers containing 2-halo-5-acetaminophenol as a coupler | SOCIETE ANONYME DITE: L'OREAL (FR) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174658-A1 | PYRIDIN-2(1H)-ONE QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS | IDH1, IDH3A, IDH2 | PKM 1742/4885SMN1; SMN2 1828/4885POLB 324/4885 |
| US-20130119359-A1 | Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element | L1CAM, ZYX, H1-0 | PKM 3336/4885SMN1; SMN2 2725/4885POLB 4147/4885 |
| US-20130123258-A1 | 4(1H)-Quinolones Having Antimalarial Activity With Reduced Chemical Resistance | CDC25C, ABCC1, CDC25A | PKM 834/4885SMN1; SMN2 2640/4885POLB 613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.