Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 3/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633650 | 0.91 | LMNA (0.44) | PAOXLMNANAAADNM1KDM5A | |
| SCHEMBL31204053 | 0.88 | PAOX (0.46) | PAOXLMNAS1PR2S1PR4S1PR1 | |
| SCHEMBL31204082 | 0.88 | PAOX (0.46) | PAOXLMNAS1PR2S1PR4S1PR1 | |
| SCHEMBL31203946 | 0.88 | PAOX (0.46) | PAOXLMNAS1PR2S1PR4S1PR1 | |
| SCHEMBL31204187 | 0.88 | PAOX (0.46) | PAOXLMNAS1PR2S1PR4S1PR1 | |
| SCHEMBL31203981 | 0.88 | PAOX (0.46) | PAOXLMNAS1PR2S1PR4S1PR1 | |
| SCHEMBL9633089 | 0.86 | PAOX (0.42) | PAOXLMNAS1PR2S1PR4S1PR1 | |
| SCHEMBL8778535 | 0.84 | LMNA (0.50) | LMNAKDM5APHF8KDM4CALDH1A1 | |
| Dodecanol SCHEMBL9777570 | 0.82 | LMNA (0.61) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL25412654 | 0.82 | PAOX (0.46) | PAOXS1PR2S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |