Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633491 | 0.91 | PAOX (0.48) | LMNADNM1PAOXKDM5APHF8 | |
| SCHEMBL9633196 | 0.91 | DNM1 (0.43) | DNM1PAOXKDM5APHF8KDM4C | |
| SCHEMBL1914764 | 0.87 | KDM5A (0.43) | KDM5APHF8KDM4CHDAC11ALDH1A1 | |
| SCHEMBL9722887 | 0.85 | KDM5A (0.43) | KDM5APHF8KDM4CHDAC11ALDH1A1 | |
| SCHEMBL25412654 | 0.84 | PAOX (0.46) | DNM1PAOXKDM5APHF8KDM4C | |
| Hydrochloric Acid SCHEMBL9722886 | 0.84 | KDM4C (0.42) | KDM5APHF8KDM4CHDAC11ALDH1A1 | |
| SCHEMBL9633174 | 0.84 | LMNA (0.41) | LMNADNM1PAOXKDM5APHF8 | |
| SCHEMBL25724104 | 0.83 | LMNA (0.54) | LMNAHDAC11CNR1ALDH1A1CNR2 | |
| SCHEMBL8565188 | 0.83 | LMNA (0.54) | LMNAHDAC11CNR1ALDH1A1CNR2 | |
| SCHEMBL9935060 | 0.83 | LMNA (0.54) | LMNAHDAC11CNR1ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |