Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1412207 | 0.83 | ACACB (0.59) | LDHAACACB | |
| SCHEMBL21959086 | 0.81 | MEN1 (0.54) | LDHA | |
| SCHEMBL15468319 | 0.78 | PKM (0.47) | PKMLDHAACACBADRB2TAS1R3 | |
| SCHEMBL10079224 | 0.77 | PKM (0.46) | PKMLDHAACACBADRB2TAS1R3 | |
| SCHEMBL6677141 | 0.76 | ACACB (0.52) | LDHAACACB | |
| SCHEMBL6677138 | 0.76 | ACACB (0.52) | LDHAACACB | |
| SCHEMBL9632397 | 0.76 | ADRA1D (0.50) | PKMADRB2PPARG | |
| SCHEMBL6541208 | 0.76 | CNR1 (0.56) | PKMLDHAACACB | |
| SCHEMBL4362047 | 0.75 | ACACB (0.51) | LDHAACACB | |
| SCHEMBL4362055 | 0.75 | ACACB (0.51) | LDHAACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331943-B1 | PHENOXYETHYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND COMPOSITION FOR EXHIBITING EXCELLENT ALPHA-1-BLOCKING ACTIVITY CONTAINING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-4971990-A | HYPOTENSIVE AGENTS, DYSUREA | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0331943-A1 | Phenoxyethylamine derivatives, process for preparing the same, and composition for exhibiting excellent alpha-1-blocking activity containing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1989-09-13 | — | — | EP | disclosed |