Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1412207 | 0.83 | ACACB (0.59) | LDHA | |
| SCHEMBL21880004 | 0.82 | ESR1 (0.60) | MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL7650354 | 0.81 | ESR1 (0.44) | MEN1KMT2A | |
| SCHEMBL9634012 | 0.81 | PKM (0.49) | LDHA | |
| SCHEMBL21959543 | 0.78 | ESR1 (0.68) | LDHANPSR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28884388 | 0.78 | CNR1 (0.69) | MEN1KMT2ANPSR1CNR1 | |
| SCHEMBL6677141 | 0.76 | ACACB (0.52) | LDHA | |
| SCHEMBL6677138 | 0.76 | ACACB (0.52) | LDHA | |
| SCHEMBL6541208 | 0.76 | CNR1 (0.56) | LDHACNR1 | |
| SCHEMBL9463780 | 0.74 | LDHA (0.73) | LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11453632-B2 | 1-phenyl-2-phenylethane derivative | KAO CORPORATION (JP) | 2022-09-27 | — | — | US | disclosed |
| US-20220009869-A1 | 1-PHENYL-2-PHENYLETHANE DERIVATIVE | KAO CORPORATION (JP) | 2022-01-13 | — | — | US | disclosed |
| WO-2020085373-A1 | 1-PHENYL-2-PHENYLETHANE DERIVATIVE | 花王株式会社 | 2020-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009869-A1 | 1-PHENYL-2-PHENYLETHANE DERIVATIVE | ESR2, GPER1, ESR1 | MEN1 3654/4885KMT2A 419/4885LDHA 4622/4885 |
| US-11453632-B2 | 1-phenyl-2-phenylethane derivative | ESR2, GPER1, ESR1 | MEN1 3654/4885KMT2A 419/4885LDHA 4622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.