Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455586 | 0.76 | PKM (0.39) | ALDH1A1PKMKDM4EPTGER2NFE2L2 | |
| SCHEMBL27469362 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL4759310 | 0.72 | CA12 (0.50) | ALDH1A1PKMKDM4EKMT2A | |
| SCHEMBL27469364 | 0.72 | ALDH1A1 (0.50) | ALDH1A1PKMKMT2AL3MBTL1 | |
| SCHEMBL9750530 | 0.71 | PKM (0.40) | ALDH1A1PKMKDM4EPTGER2NFE2L2 | |
| SCHEMBL28634012 | 0.69 | KDM4E (0.41) | ALDH1A1PKMKDM4ENFE2L2KMT2A | |
| SCHEMBL2810981 | 0.69 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2AL3MBTL1POLB | |
| SCHEMBL5901579 | 0.68 | POLB (0.50) | ALDH1A1PKMKDM4EKEAP1NFE2L2 | |
| SCHEMBL9370312 | 0.68 | L3MBTL1 (0.49) | PKMKDM4EL3MBTL1MAOAMAOB | |
| SCHEMBL30498943 | 0.68 | TSHR (0.50) | ALDH1A1PKMKDM4ENFE2L2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298915-B1 | PYRIDYLTHIO-, PYRIDYLSULFINYL- AND PYRIDYLSULFONYL-PHENYL-THIOUREAS, ISOTHIOUREAS AND CARBON DIIMIDES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1992-05-20 | — | — | EP | disclosed |
| EP-0298915-A1 | Pyridylthio-, pyridylsulfinyl- and pyridylsulfonyl-phenyl-thioureas, isothioureas and carbon diimides, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1989-01-11 | — | — | EP | disclosed |
| EP-0298915-A1 | Pyridylthio-, pyridylsulfinyl- and pyridylsulfonyl-phenyl-thioureas, isothioureas and carbon diimides, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1989-01-11 | — | — | EP | disclosed |