Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633717 | 0.92 | KMT2A (0.46) | KMT2AFKBP1AHTTALDH1A1MTNR1A | |
| SCHEMBL9633847 | 0.85 | EPHX2 (0.47) | — | |
| SCHEMBL9633121 | 0.81 | PLA2G4A (0.42) | KMT2APLA2G4AMTNR1AMTNR1B | |
| SCHEMBL9634189 | 0.80 | PLA2G4A (0.41) | KMT2APLA2G4AMTNR1AMTNR1B | |
| SCHEMBL9634171 | 0.78 | PLA2G4A (0.53) | HTTPLA2G4A | |
| SCHEMBL9634320 | 0.77 | CYP1A2 (0.50) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL9634717 | 0.73 | PLA2G4A (0.51) | PLA2G4AMTNR1AMAPK1 | |
| SCHEMBL9634970 | 0.73 | NQO2 (0.49) | KMT2AMEN1PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL9633818 | 0.73 | NQO2 (0.42) | KMT2AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL9633707 | 0.72 | KMT2A (0.41) | KMT2AALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337765-B1 | ACYLSULFONAMIDE DERIVATIVES OF ALPHA-CARBOCYCLYLTOLUIC ACIDS USED AS LEUKOTRIENE ANTAGONISTS | ICI AMERICAS INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| US-5095038-A | Antiinflammatory, antiallergens | ICI AMERICAS INC. (US) | 1992-03-10 | — | — | US | disclosed |
| EP-0337765-A2 | Acylsulfonamide derivatives of alpha-carbocyclyltoluic acids used as leukotriene antagonists | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |