SCHEMBL9634245

SCHEMBL9634245

CCOC(=O)NC(=S)NC(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
ALDH1A1 P00352 6/20 0.40
ALOX12 P18054 4/20 0.40
LMNA P02545 5/20 0.39
HPGD P15428 3/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GAA P10253 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
CXCR2 P25025 1/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
HTT P42858 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12890240 0.80 ALDH1A1 (0.40) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL906813 0.79
SCHEMBL10634574 0.78 ALDH1A1 (0.45) MAPTALDH1A1ALOX12LMNAGAA
SCHEMBL18591543 0.78 MAPT (0.42) MAPTALDH1A1LMNAGAACXCR2
SCHEMBL4429650 0.76 FPR2 (0.38) MAPTALDH1A1LMNAKMT2AGAA
SCHEMBL18612045 0.76 MAPT (0.41) MAPTALDH1A1LMNAKMT2AGAA
SCHEMBL8585563 0.76 SMN1; SMN2 (0.42) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL5455357 0.76 ALDH1A1 (0.48) MAPTALDH1A1ALOX12LMNAMEN1
SCHEMBL11697695 0.74 MMP8 (0.49) MAPTALDH1A1LMNAGAASMN1; SMN2
SCHEMBL25693458 0.74 ATM (0.52) ALDH1A1ALOX12LMNAGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5147572-A Metal salt of phosphorus acid derivative, dithiocarbamate THE LUBRIZOL CORPORATION (US) 1992-09-15 US disclosed
US-5094746-A Metal salt of a phosphorus acid, a dithiocarbamate and a thionocarbamate THE LUBRIZOL CORPORATION (US) 1992-03-10 US disclosed
WO-1991019569-A1 ORE FLOTATION PROCESS USING CARBAMATE COMPOUNDS THE LUBRIZOL CORPORATION (US) 1991-12-26 WO disclosed
US-5037533-A Ore flotation process and use of phosphorus containing sulfo compounds THE LUBRIZOL CORPORATION (US) 1991-08-06 US disclosed
US-5015368-A Ore flotation process using carbamate compounds THE LUBRIZOL CORPORATION (US) 1991-05-14 US disclosed
US-4879022-A BENEFICATION THE LUBRIZOL CORPORATION (US) 1989-11-07 US disclosed
EP-0324833-A1 PROCESS FOR BENEFICIATION OF SULFIDE ORES BY FROTH FLOTATION The Lubrizol Corporation (US) 1989-07-26 EP disclosed
WO-1989000457-A1 PROCESS FOR BENEFICIATION OF SULFIDE ORES BY FROTH FLOTATION THE LUBRIZOL CORPORATION (US) 1989-01-26 WO disclosed
US-RE32786-E FROTH FLOTATION, BENEFICIATION OF ORES AMERICAN CYANAMID COMPANY (US) 1988-11-22 US disclosed
US-4659853-A Process for the production of isothiocyanate derivatives AMERICAN CYANAMID COMPANY (US) 1987-04-21 US disclosed
US-4556482-A ADDING FROTHING AGENT AND METAL COLLECTOR TO AN AQUEOUS SLURRY OF ORE PARTICLES AMERICAN CYANAMID COMPANY (US) 1985-12-03 US disclosed
US-4556483-A FROTH FLOTATION PROCESS FOR THE RECOVERY OF METAL ORES AMERICAN CYANAMID COMPANY (US) 1985-12-03 US disclosed