Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858630 | 0.83 | FPR2 (0.43) | FPR2NOD1MMEFOLH1SIRT2 | |
| Hydrochloric Acid SCHEMBL27527505 | 0.82 | FPR2 (0.42) | FPR2NOD1MMEFOLH1SIRT2 | |
| SCHEMBL12291691 | 0.81 | FPR2 (0.46) | FPR2NOD1GAAPOLBMAPT | |
| SCHEMBL27754766 | 0.80 | FPR2 (0.41) | FPR2NOD1MMEFOLH1SIRT2 | |
| SCHEMBL9634245 | 0.76 | MAPT (0.40) | GAAMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL9832048 | 0.73 | NOD1 (0.49) | NOD1MMESIRT2SIRT1CTSS | |
| SCHEMBL9832042 | 0.73 | NOD1 (0.49) | NOD1MMESIRT2SIRT1CTSS | |
| SCHEMBL10146967 | 0.73 | FPR2 (0.49) | FPR2NOD1MAPTALDH1A1MME | |
| SCHEMBL6269749 | 0.72 | NOD1 (0.51) | NOD1MAPTFOLH1SIRT2SIRT1 | |
| SCHEMBL5455357 | 0.72 | ALDH1A1 (0.48) | GAAMAPTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125739-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008079371-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |