SCHEMBL9634503

SCHEMBL9634503

C=CC(=O)NCc1ccc(O)cc1C

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 2/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 1/20 0.43
AIMP2 Q13155 1/20 0.40
MAOB P27338 1/20 0.40
EPHX2 P34913 1/20 0.39
EGFR P00533 1/20 0.37
BTK Q06187 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5082960 0.86 NPC1 (0.55) TGM2NPC1RAB9AGAAKMT2A
SCHEMBL29157949 0.81 EGFR (0.49) TGM2EGFRALDH1A1TDP1
SCHEMBL27965029 0.79 TGM2 (0.41) TGM2NPC1RAB9AGAAKMT2A
SCHEMBL5082541 0.79 KMT2A (0.67) TGM2NPC1RAB9AGAAKMT2A
SCHEMBL11204026 0.77 BTK (0.53) TGM2NPC1RAB9AGAAKMT2A
SCHEMBL10784544 0.76 GAA (0.43) TGM2NPC1RAB9AGAAKMT2A
SCHEMBL11209573 0.76 GAA (0.45) NPC1RAB9AGAAKMT2AEGFR
SCHEMBL18636751 0.75 TGM2 (0.44) TGM2NPC1RAB9AGAAKMT2A
SCHEMBL27965025 0.75 TGM2 (0.44) TGM2GAAKMT2AMAOBBTK
SCHEMBL27965326 0.75 HTT (0.43) TGM2NPC1RAB9AGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0203465-B1 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1992-07-15 EP disclosed
US-4752561-A Light-sensitive silver halide photographic material incorporating metal complex with high quenching constant and an oil soluble dye KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-06-21 US disclosed
EP-0203465-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1986-12-03 EP disclosed
US-4414308-A Silver halide color photographic photosensitive material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1983-11-08 US disclosed
US-4409321-A COLOR PHOTOGRAPHY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1983-10-11 US disclosed